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An Abstract on Malaria Infection


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Almost every, one time or the other, if not all their lifetime has been diagnosed of malaria infection. Some has gone to the extent of taking if as their ailment by calling it “my malaria”. This project is design to educate people on the pathogenesis of the malaria parasite, on the two major classification of malaria infection, the clinical features of the four plasmodium species (plasmodium falciparum, vivax, malariae, ovela) that causes malaria infection, to explain how malaria parasite hides from the immune system, on health education and prevention of malaria infection, treatment of malaria infection and why their hasn’t been a vaccine for malaria infection, also why there has been increase in antimalaria drug resistance.

Malaria infection can be either uncomplicated or severe. It said to be severe when plasmodium falciparum is the cause of the infection. The life cycle of the parasite (pathogenesis) is so complicated because of the tendency of the merozoite (daughter cell of the parasite) to produce different antigen that are sensitive to different antibody. This has made the production of the vaccine against it difficult and also making it possible for it to hide from the immune system. There has been an increase in antimmalaria drug resistance because many have abused malaria drugs. This has lead to combination therapy kin of treatment instead of monotherapy. The prevention of malaria infection is simply preventing the malaria vector (anopheles mosquito) from biting people and making sure that there is no stagnant water around our homes.

This project, which is on designing an expert system for diagnosis and treatment of malaria has in its chapter one, introduction, background of study, why an expert system is needed for the treatment of malaria etc. Chapter two which is the literature review has some quotes from different authors on parasites and malaria, example of such book is Davidson’s Principles and Practice of Medicine. It also contains the pathogenesis (life cycle) of the malaria parasite, classification of malaria, how malaria parasite hides from the immune system, vaccine against malaria, signs and symptoms and treatment as well as health education and prevention of malaria infection etc. chapter three is the system analysis. An analysis of the existing system was made and it’s loop holes were stated as well as solution to such loop holes were proffered. Chapter four is the system design and implementation, while five is the summary, conclusion and recommendation.


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